Received: January 18, 2011
Accepted: March 03, 2011
Ref: Kumar N, Bylappa K, Ramesh AC, Swetha R. A study of eosinophil count in nasal and blood smear in allergic respiratory diseases in a rural setup. Internet J Med Update. 2012 Jan;7(1):40-6.
A STUDY OF EOSINOPHIL COUNT IN NASAL AND BLOOD SMEAR IN ALLERGIC RESPIRATORY DISEASES IN A RURAL SETUP
Naveen Kumar* MD, Kiran Bylappa† MS, Ramesh AC‡ MD and Swetha Reddy** MBBS
*Assistant Professor, Department of Pediatrics, Sri Devarj Urs Medical College & Hospital. Tamaka, Kolar, Karnataka, India
†Assistant Professor, Department of Otorhinolaryngology, Sapthagiri Institute of Medical Sciences & Research Center, Bengaluru, Karnataka, India
‡Professor, Department of Pediatrics, Kempegowda Institute of Medical Sciences, Bengaluru, Karnataka, India
**Junior Resident, Department of Pediatrics, M. R. M. C. Gulbarga, Karnataka, India
(Corresponding Author: Dr Kiran Bylappa, #24, 7th main road Vasanthanagar, Bangalore 560052, Karnataka, India; Mobile: 09945690149; Email: firstname.lastname@example.org)
Allergic respiratory disorders are fairly common visiting cases in pediatrics outpatient department (OPD). With an appropriate history and detailed examination, diagnosis may not be problematic. Routine investigation may not contribute much to the final diagnosis but may help in ruling out other possibilities. This study was done to evaluate sensitivity and specificity of blood or nasal eosinophilia in subjects suffering from allergic respiratory disorders and also to assess the feasibility of nasal cytogram which is a simple, economical and reliable investigation in allergic respiratory disorders. This is a prospective clinical correlation study of patients attending outpatient department. 100 subjects aged between 2-18 years of either sex were selected for the estimation of eosinophil count in nasal and peripheral smear in allergic respiratory disorders. All allergic respiratory cases based on eosinophillia. The nasal and blood eosinophilia were compared with each other and clinical findings of allergic rhinitis with or without asthma were studied. In this study peak age incidence was seen between 11-18 years and it was more common in males. Rhinorrhoea, pale mucosa and nasal obstruction were common findings in allergic rhinitis with bronchial asthma. Nasal eosinophilia was seen in 52.4% and 64.9% of cases of allergic rhinitis and allergic rhinitis with asthma respectively. Blood eosinophilia was seen in 54% and 56.8% of cases of allergic rhinitis with asthma respectively. Nasal cytogram which is a simple, economical and non- invasive procedure can be used as an alternative to invasive peripheral smear eosinophilia as both are equally efficacious in diagnosing allergic respiratory diseases.
KEY WORDS: Eosinophilia; Allergic rhinitis; Bronchial asthma